Volunteers Sought:

Research Study Tests Medication to Treat Generalized Anxiety Disorder

Everyone knows what it is like to be anxious...but does your anxiety keep you from coping? Does it disrupt your daily life? Generalized Anxiety Disorder (GAD) is a persistent condition characterized by anxiety and exaggerated, unprovoked worry about a number of events or activities such as health, money, family, or work. It may be difficult to know where the worry is coming from. Sometimes just the thought of getting through the day provokes anxiety for people suffering from GAD.

Individuals with GAD cannot ease their concerns, even though they usually realize that their anxiety is more intense than a situation warrants. They often have trouble falling or staying asleep. Their worries may be accompanied by physical symptoms, especially trembling, twitching, muscle tension, headaches, irritability, sweating or hot flushes. Individuals with GAD may feel tired, have trouble concentrating or, sometimes suffer from depression. GAD sometimes coexists with depression, substance abuse or other anxiety disorders. Physical conditions associated with stress, such as irritable bowel syndrome, often accompany GAD.

According to the National Institute of Mental Health, approximately four million Americans suffer from GAD during the course of a given year. The disorder most often hits people in childhood or adolescence, but can begin in adulthood. It is more common in women than in men and often occurs within families.

A clinical research study is underway to test the safety and effectiveness of a novel investigational anti-anxiety medication to treat the symptoms of GAD in adults, 18 and older. Individuals who have experienced symptoms of persistent worry, anxiety and tension for at least six months may be eligible to participate in this nationwide clinical study. All volunteers who qualify for the study will receive medical care including study-related assessments and study medication. Potential study volunteers should call 1-800-STUDY-85 (extension 123).


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This story was published on May 2, 2002.